PED 6 - Pedigree Software
This is the Last Edition
New PED licenses will (probably) not be available after December 2014 for customers outside Germany
Some 20+ years ago PED was presented for the first time at an Annual Meeting of the German Society of Human Genetics. Since this time PED has been developed, slowly but continuously. PED runs on Windows XP, Vista, 7, 8, and 8.1 (Win 7-8.1 on both 32 and 64 bit versions). The last big step forward was the export of pedigree data to a format suitable for breast cancer risk assessment by BOADICEA (see below). PED / BOADICEA seem to be a great help to many geneticists counseling families with breast cancer.
So why will PED be discontinued?
On 1 January 2015, in the EU new VAT place of supply rules come into effect for business to consumer supplies of digital services (broadcasting, telecommunications and e-services). This includes software offered for download. To make a (very) long story short: This would not only involve considerable changes to this website but also lots of paperwork - not to mention an expensive EU tax expert. The implementation of the so-called "VAT mini One Stop Shop" is not supposed to be much help either. More on this, e.g., at
Not being fond of bloated bureaucracies I am extremely sorry to say that from 2015 on no more new licenses for PED will be available for customers outside Germany (please see column on the right). Maybe, when the dust has settled and a feasible solution for small businesses will come into existence new licenses (and a new version of PED) might be available.
Please note:Free support for PED will be continued.
If you have any further questions please contact me at email@example.com
Breast cancer risk assessment using PED 6 and BOADICEA
presented at the 20th Conference of the German Society of Human Genetics 2009
There are a number of models available to assess both breast cancer risk and the chances of identifying a BRCA1/2 mutation. In a recent investigation of five different carrier prediction models only the BOADICEA model predicted the overall observed number of mutations detected accurately (Antoniou et al., J Med Genet. 2008, 45:425-31). The current version of BOADICEA has been implemented as a Web-based program where users can upload a pedigree file or create a pedigree online. The online pedigree building application appears quite complicated and enables to build only simple pedigrees. However, the authors of BOADICEA claim their program will process pedigrees of any size and structure.
PED 6 (www.medgen.de) is a Windows application for creating, drawing, and editing of pedigrees. All of the pedigree drawing features conform to the Pedigree Standardization Task Force recommendations. PED 6 enables the user to export family information not only as LINKAGE or CSV (comma separated values) file, but also as a BOADICEA data file. The data files created by PED can be uploaded to the BOADICEA Web Application (BWA; www.srl.cam.ac.uk/genepi/boadicea/boadicea_home.html) to estimate the risks of breast and ovarian cancer and the probability to be a carrier of any cancer-associated mutations in the BRCA1 or BRCA2 gene.
PED 6 appears to be a valuable tool to complement the BWA. In single pedigrees risks calculated by this combination of programs differ significantly from those received by the combination of Cyrillic / LINKAGE programs currently used by the Deutsches Konsortium für Brust- und Eierstockkrebs.(PED 5: Presented at the European Congress of Human Genetics 2005)
PED 5 — Pedigree Software
PED 5 is a fast interactive Pedigree Software for Windows (R). PED was introduced at the ESHG Conference in 1997 and now has a continuously growing user community with researchers and clinicians in over 30 countries worldwide. Among other enhancements, PED 5 now can fetch family information from a data file in LINKAGE or CSV (comma separated values) format. more ...
Users from Germany: You can still order a license of PED 6 if you are located in Germany
Allerdings wird PED nicht mehr weiter entwickelt werden. Ausschlaggebend dafür waren die neuen EU-Gesetze, die seit 2015 unter anderem eine Abführung der Mehrwertsteuer in das jeweilige Land des Käufers fordern.
Innerhalb Deutschlands wird PED weiter verkauft und unterstützt werden. Neue Versionen werden aber nicht mehr erscheinen. Bei Interesse können Sie eine Standard-Lizenz für 95,00 Euro und eine Linkage - Lizenz für 145,00 Euro erwerben. Details zu PED sowie eine Test-Version stehen unter medgen.de/ped zur Verfügung.
PED 6.0.2 available
PED 6.0.2 fixes some minor issues. Especially all PED 6.0.x LINKAGE users should download this release and update PED 6. Just install into your existing PED 6.0.x directory.
Never install any PED 6 release into a PED version 5 or 4 directory!.
Notes on previous releases:
This version includes some minor bugfixes and enhancements. All
PED 5 users are encouraged to download the latest release. The upgrade
is free to all PED 5.0. and 5.1 users. Be sure to have your PED 5
registration keys available when you install PED 5.1.2. After a
successful install you can safely uninstall the previous PED 5 version.
PED has a user community now spanning more than 35 countries worldwide. Thanks a lot to all of you!
New features added in PED 5.0.5
CSV files exported from PED usually will be re-imported and displayed in less than a second, without any user interaction. On the other hand, manually created CSV files may be incorrect. PED tries to import faulty CSV files. In case there is not a single "best" solution, PED allows to choose from several possible "consultands" as a starting point for a pedigree drawing.
PED 5 release
December 4, 2005
Now you can import / export in a format suitable for import into a database, or linkage analysis. The size of your data does not matter as long as you adhere to a simple rule of thumb: what can be drawn in the PED input window also can be imported from a data file.